Ursodiol (Ursodeoxycholic acid) 300 mg
Important Information
It may take several months for ursodiol to work. Do not stop taking ursodiol without checking with your doctor.
Lab tests, including liver function, may be performed while you use ursodiol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Ursodiol should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
Ursodiol Uses
Ursodiol is used to dissolve certain types of gallstones, to prevent gallstones from forming in obese patients who are losing weight rapidly, and to treat a certain type of liver disease (primary biliary cirrhosis). Ursodiol is a bile acid.
How To Use Ursodiol
Use ursodiol as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take ursodiol by mouth with food or milk.
- Do not take an antacid that has aluminum in it or a bile acid sequestrant (eg, cholestyramine, colestipol) within 1 hour before or 2 hours after you take ursodiol.
- If you miss a dose of ursodiol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use ursodiol.
Before Taking Ursodiol
- Tell your doctor and pharmacist if you are allergic to ursodiol, bile acids, or any other drugs.
- Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antacids that contain aluminum (Amphojel, Gaviscon, Maalox, Mylanta, others), cholestyramine (LoCHOLEST, Prevalite, Questran), clofibrate (Atromid-S), colestipol (Colestid), medications that lower lipid or cholesterol levels, medications that contain estrogen (including birth control pills), and vitamins and herbal products.
- Tell your doctor if you have or have ever had disease of the liver, gallbladder, pancreas, or bile duct.
- Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ursodiol, call your doctor.
Side Effects Of Ursodiol
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
- diarrhea
- constipation
- upset stomach
- indigestion
- dizziness
- vomiting
- cough
- sore throat
- runny nose
- back pain
- muscle and joint pain
- hair loss
Drug Description
URSO 250 (ursodiol, 250 mg) is available as a film-coated tablet for oral administration. URSO Forte (ursodiol, 500 mg) is available as a scored film-coated tablet for oral administration. Ursodiol (ursodeoxycholic acid, UDCA) is a naturally occurring bile acid found in small quantities in normal human bile and in larger quantities in the biles of certain species of bears. It is a bitter-tasting white powder consisting of crystalline particles freely soluble in ethanol and glacial acetic acid, slightly soluble in chloroform, sparingly soluble in ether, and practically insoluble in water.
Inactive ingredients: microcrystalline cellulose, povidone, sodium starch glycolate, magnesium stearate, ethylcellulose, dibutyl sebacate, carnauba wax, hydroxypropyl methylcellulose, PEG 3350, PEG 8000, cetyl alcohol, sodium lauryl sulfate and hydrogen peroxide.
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