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PREMARIN (CONJUGATED ESTROGENS)
Premarin
Information
Premarin
is a member of the Conjugated Estrogens group of drugs, based on the female sex
hormone estrogen. Estrogen is a hormone essential to the female physiology, on
which many of the female-specific body function are based. Among the disorders
that may occur when the estrogen quantity becomes insufficient, some examples
are: menopause, infertility, and someBreast Cancer types, and ovary
function deficiencies, degeneration of the vagina or urethra. The male human
body also needs estrogen to function properly, insufficient quantities of this
hormone leading to prostate cancer.
Premarin
Indications
Premarin
is mainly prescribed for the treatment of such disorders as:
- moderate or severe vasomotor symptoms associated with the menopause
- moderate or severe symptoms of vaginal or vulvar atrophy associated with the menopause
- hypoestrogenism due to hypogonadism, castration or primary ovarian failure
- some types of Breast Cancer
- advanced androgen-dependent carcinoma of the prostate
- prevention of postmenopausal osteoporosis – in carefully selected cases.
There
are a number of other cases in which Premarin can be prescribed, so if you want
to know more about why you have been prescribed this drug, consult your
personal health care specialist.
Premarin
Warnings
Consult
with your personal health care specialist before starting to take Premarin if
you are suffering of blood clotting and circulation disorders, abnormal vaginal
bleedings, cancer of the breast, uterus or any type of hormone-dependent
cancer, as treatment with Premarin might be dangerous in such cases. Also,
special care, monitoring or altered dosages may be required for patients that are
suffering or have medical history of:
- Uterine fibroids
- Gall bladder diseases
- Diabetes
- Migraines
- Epilepsy
- Asthma
- Kidney related disorders
- Liver related disorders
- High level of Bad cholesterol in triglycerides in the blood
- hypertension, angina or any heart disorders
- Hysterectomy
This
drug has been in a number of cases considered to be the main cause of malformed
fetus development. Use of this drug is hazardous to an unborn child, so you
should never take Premarin if you are pregnant or planning to become a mother
soon. Also, Premarin may affect breast milk flow and composition, so it is
advised that you should consult with your personal health care specialist
before starting on this drug if you are a nursing mother.
It is also strongly advised that Premarin be prescribed at the lowest dosage and for the shortest time possible, as prolonged treatment or high dosage of this medicine can cause a number of other hormone related diseases.
It is also strongly advised that Premarin be prescribed at the lowest dosage and for the shortest time possible, as prolonged treatment or high dosage of this medicine can cause a number of other hormone related diseases.
Closely
follow the intake guidelines that your personal health care supervisor has
given you. Should you have any trouble understanding any of the guidelines,
please ask a doctor, pharmacist or nurse to help you. It is recommended that
the Premarin dose should be accompanied by a glass of water, and preferably be
taken on a full stomach to reduce stomach upset. Store away from heat and
moisture, in a safe place, away from the reach of children.
Premarin
Dosage
Consult
your personal health care specialist to obtain the Premarin dosage best suited
to your age and general health condition. Self-medication should never be
employed when starting a treatment with this medicine. Never alter the dosage
you have been given by your physician, either by modifying the drug quantity or
the time interval between intakes.
One
of the most serious side effects associated with Premarin treatment is the increased
risk of developing cancer of the uterus, through development
of endometrial hyperplasia. However, this effect can be countered by
taking progestins.
Other serious side effects of Premarin use are:
Other serious side effects of Premarin use are:
- Increased risk of heart attacks or stroke
- Increased chance of developing Breast Cancer
- Increased chance of developing blood clots in the lungs or legs
- Allergic reactions (such as difficulty breathing, hives, rashes, swelling of the face, tongue or lips)
- Chest pains, shortness of breath
- Painful swollen legs
- Abnormal vaginal bleeding
- Pain, tenderness and swelling of the abdomen
- Severe headaches, blurred vision, trouble in speech, dizziness
- Jaundice
- Breast lumps
Should
you happen to experience any of the above symptoms, immediately stop Premarin
use and contact your personal health care specialist.
Other side effects that may occur, with less grave consequences, are:
Other side effects that may occur, with less grave consequences, are:
- Nausea
- Swollen or tender breasts
- Acne or skin changes
- A decrease in the sex drive
- Headaches, migraines
- Bloating through water retention
- Depression
- Changes in the menstrual cycle
Should
you experience any of these, consult your health care specialist to establish
the appropriate course of action.
Premarin
Drug Reactions
There
are a few drugs that are known to interact with Premarin. The most commonly used
of them are:
- Anticoagulants
- Levothyroxine
- Insulin, or other diabetes related medicines (such as Glipizide or Glyburide)
- Tamoxifen
- Didanosine
- Phenytoin
- Carbamezepine
- Phenobarbital
- Primidone
- Rifampin
If
you are under treatment with any of these drugs, or have recently finished
treatment with any of them, please talk with your personal health care
specialist as he may decide to alter your Premarin dosage and / or keep you
under special monitoring for the duration of the treatment.
Buy
Premarin. It is available through our Online Pharmacy or at any Canada Pharmacy
selling Online Prescriptions. In some countries PREMARIN may also be known
as: Belestar, Livomarin, Estrogenon, Estroplus, Menosedan, Prem, Repogen, CES,
Climatrol E, Conpremin, Estrarona, Oestrofeminal, Climopax mono, Equin, Espauz,
Estrin, Dagynil, Longaplex, Cenestin, Enjuvia, Biostrogen, Climatrol E,
Menostat
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